{"id":223,"date":"2016-10-18T16:16:26","date_gmt":"2016-10-18T16:16:26","guid":{"rendered":"https:\/\/halopharma.com\/how-we-help-2\/large-pharmaceutical\/"},"modified":"2025-08-25T10:39:19","modified_gmt":"2025-08-25T14:39:19","slug":"large-pharma","status":"publish","type":"page","link":"https:\/\/halopharma.com\/fr\/who-we-help\/large-pharma\/","title":{"rendered":"Large Pharma"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"223\" class=\"elementor elementor-223\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-23d3daf4 e-flex e-con-boxed e-con e-parent\" data-id=\"23d3daf4\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7b83e806 e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"7b83e806\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;background_motion_fx_motion_fx_scrolling&quot;:&quot;yes&quot;,&quot;background_motion_fx_translateX_effect&quot;:&quot;yes&quot;,&quot;background_motion_fx_translateX_direction&quot;:&quot;negative&quot;,&quot;animation&quot;:&quot;fadeIn&quot;,&quot;background_motion_fx_translateX_speed&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:4,&quot;sizes&quot;:[]},&quot;background_motion_fx_translateX_affectedRange&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:{&quot;start&quot;:0,&quot;end&quot;:100}},&quot;background_motion_fx_devices&quot;:[&quot;desktop&quot;,&quot;tablet&quot;,&quot;mobile&quot;]}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6ac36a39 elementor-invisible elementor-widget elementor-widget-image\" data-id=\"6ac36a39\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;slideInLeft&quot;,&quot;_animation_delay&quot;:500}\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"406\" src=\"https:\/\/halopharma.com\/wp-content\/uploads\/2025\/08\/HowWeHelp_LargePharma-rs.webp\" class=\"attachment-large size-large wp-image-3139\" alt=\"\" srcset=\"https:\/\/halopharma.com\/wp-content\/uploads\/2025\/08\/HowWeHelp_LargePharma-rs.webp 800w, https:\/\/halopharma.com\/wp-content\/uploads\/2025\/08\/HowWeHelp_LargePharma-rs-300x152.webp 300w, https:\/\/halopharma.com\/wp-content\/uploads\/2025\/08\/HowWeHelp_LargePharma-rs-768x390.webp 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-213c318f e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"213c318f\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4904cf4a elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"4904cf4a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<h4>Halo Pharma has extensive experience in clinical trial drug product manufacturing for tomorrow\u2019s most important medicines.<\/h4>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-21c8a881 e-flex e-con-boxed e-con e-parent\" data-id=\"21c8a881\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-51f9314c elementor-widget elementor-widget-text-editor\" data-id=\"51f9314c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Halo Pharma has over 10 years of clinical and commercial scale contract drug product development and manufacturing experience with multinational and large pharma companies.<\/p><p>Halo\u2019s leadership team has over 200 years of combined experience in drug product development and manufacturing.\u00a0We partner with our clients to provide technical development solutions to address the increased pressure to meet pipeline timelines and budgets.<\/p><p>Halo Pharma has successfully supported over 100 new product launches in the past 10 years.<\/p><p>We support 8 of the top 10 large pharmaceutical companies by market cap and have developed and manufactured products for more than 20 NDA applications. At any given time we have over 20 active clinical stage products in our Product Development Services pipeline so our scientists and technicians are constantly refreshing their expertise in working with some of the most challenging molecules. \u00a0Many Large Pharma clients work with us for line extensions in particular, for pediatric indications.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2cee52b0 elementor-widget elementor-widget-heading\" data-id=\"2cee52b0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">A Focus on Trust and Partnership\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1bbf6645 elementor-widget elementor-widget-text-editor\" data-id=\"1bbf6645\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>We partner with our clients to provide technical development solutions to address the increased pressure to meet pipeline timelines and budgets. We can provide expertise in the development of drug product candidates and commercial technical transfers that cover a wide array of therapeutic areas for adult and pediatric dosage forms including orphan drugs with particular expertise in cardiovascular, CNS, dermatologic and pain management products.<\/p><p>We provide our clients flexible, quality led\u00a0<a href=\"https:\/\/halopharma.com\/capabilities\/formulation-development\/\">development<\/a>\u00a0and\u00a0<a href=\"https:\/\/halopharma.com\/capabilities\/commercial-manufacturing\/\">commercialization<\/a>\u00a0solutions with specialization in the development of:<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-658dacd e-grid e-con-boxed e-con e-parent\" data-id=\"658dacd\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-da49b8a elementor-widget elementor-widget-text-editor\" data-id=\"da49b8a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<ul class=\"two-column\"><li>Poorly Water Soluble Drugs using state of the art Hot-Melt or Twin Screw Extrusion Technologies<\/li><li>Difficult to formulate, high dose anti-infective products using our extensive roller compaction capabilities<\/li><li>Pediatric Drug Products including Mini and MicroTablets, Pellets Beads, Powders, Capsules, Stick Pack and Liquid Suspensions<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ed2278e elementor-widget elementor-widget-text-editor\" data-id=\"ed2278e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<ul class=\"two-column\"><li>Topical Sterile and Non-Sterile Semi-Solid Ointments, Gels &amp; Creams<\/li><li>Pain &amp; Abuse Deterrent dosage forms including Modified Release\u00a0<a href=\"https:\/\/halopharma.com\/our-facilities\/whippany-nj\/controlled-substances-whippany\/\">Controlled Substances<\/a>\u00a0(CI-CV) and Fixed-Dose Combination (FDC) products<\/li><li>CNS products including Bi-Layer and Orodispersible tablets and with specific capabilities in Granulation\/Wurster coating including the use of solvents<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-05b2f41 e-flex e-con-boxed e-con e-parent\" data-id=\"05b2f41\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-725eb0b elementor-widget elementor-widget-text-editor\" data-id=\"725eb0b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>We have developed many difficult to formulate drug products and provide bioavailability solutions to meet critical clinical endpoints.<\/p><p>Our Large Pharma Partners benefit from a single Project Team providing continuity as products progress through the following stages that include:<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1ed48ed e-grid e-con-boxed e-con e-parent\" data-id=\"1ed48ed\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3a0c542 elementor-widget elementor-widget-text-editor\" data-id=\"3a0c542\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<ul class=\"two-column\"><li>Analytical Development, Transfer and Validation Activities<\/li><li>Drug Development and Formulation Technical Transfer<\/li><li>Manufacturing Non-GMP Laboratory Batches &amp; Stability Programs<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2a1d901 elementor-widget elementor-widget-text-editor\" data-id=\"2a1d901\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<ul class=\"two-column\"><li>QbD Optimization Batches<\/li><li>cGMP Pilot Batches (Pharmacokinetics-Bio Batches)<\/li><li>cGMP Pivotal Batches (Bioequivalence Batches)<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6f1cef7 e-flex e-con-boxed e-con e-parent\" data-id=\"6f1cef7\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c8d14a7 elementor-widget elementor-widget-text-editor\" data-id=\"c8d14a7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Our integrated pharmaceutical development solutions are customized to focus on your program needs, which can include:<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-667d76f e-grid e-con-boxed e-con e-parent\" data-id=\"667d76f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d9a9783 elementor-widget elementor-widget-text-editor\" data-id=\"d9a9783\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<ul class=\"two-column\"><li>505 (b) (2) pathway for oral modified specialty products<\/li><li>Orphan drugs for rare diseases<\/li><li>Technical Transfer of in-licensed late stage products<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-55b89dd elementor-widget elementor-widget-text-editor\" data-id=\"55b89dd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"fusion-text fusion-text-1\"><ul class=\"two-column\"><li>New indications or novel drug delivery formulation of exiting products<\/li><li>Product Line-Extensions (Pediatric dosage form for an Adult dosage form)<\/li><\/ul><\/div><div class=\"fusion-reading-box-container reading-box-container-2\"><div class=\"reading-box\">\u00a0<\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-305252b e-flex e-con-boxed e-con e-parent\" data-id=\"305252b\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f5ee343 elementor-widget elementor-widget-heading\" data-id=\"f5ee343\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">Halo Pharma has been commercially approved in both the US and Europe to produce two Orphan Drugs in the last 3 years and has several more in development.<\/h5>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Halo Pharma has extensive experience in clinical trial drug product manufacturing for tomorrow\u2019s most important medicines. Halo Pharma has over 10 years of clinical and commercial scale contract drug product development and manufacturing experience with multinational and large pharma companies. Halo\u2019s leadership team has over 200 years of combined experience in drug product development and [&hellip;]<\/p>\n","protected":false},"author":25,"featured_media":0,"parent":221,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-223","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/halopharma.com\/fr\/wp-json\/wp\/v2\/pages\/223","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/halopharma.com\/fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/halopharma.com\/fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/halopharma.com\/fr\/wp-json\/wp\/v2\/users\/25"}],"replies":[{"embeddable":true,"href":"https:\/\/halopharma.com\/fr\/wp-json\/wp\/v2\/comments?post=223"}],"version-history":[{"count":12,"href":"https:\/\/halopharma.com\/fr\/wp-json\/wp\/v2\/pages\/223\/revisions"}],"predecessor-version":[{"id":3142,"href":"https:\/\/halopharma.com\/fr\/wp-json\/wp\/v2\/pages\/223\/revisions\/3142"}],"up":[{"embeddable":true,"href":"https:\/\/halopharma.com\/fr\/wp-json\/wp\/v2\/pages\/221"}],"wp:attachment":[{"href":"https:\/\/halopharma.com\/fr\/wp-json\/wp\/v2\/media?parent=223"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}